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Not only is GSH regulated by Nrf2, the thioredoxin-based antioxidant system (TXN1, TXNRD1) is also regulated by Nrf2, indicating that Nrf2 regulates the redox state of proteins (Reisman et al., 2009)

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Copper ions naturally accelerate oxidation, and vitamin C is extremely prone to oxidation

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Pharmaceuticals 17 (1), 54

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and safe titration of high-alert medications

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