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Advertisement Article continues below this ad Considerations Some weight-loss programs offer or recommend vitamin B-12 injections to boost metabolism

This systematic review and meta-analysis aimed to evaluate and compare the effectiveness of sublingual and oral vitamin B12 administration in comparison with intramuscular (IM) injections, both for improving serum cobalamin and reducing homocysteine levels

[4] However, consistently taking large amounts of vitamins from multiple sources could potentially increase the risk of side effects (for example, very high vitamin B intake from multiple supplements over time can cause neuropathy, and high niacin from many sources could affect your liver)