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It is designed for patients experiencing burning, tingling, or numbness in the extremities, slow wound healing, microvascular dysfunction, or inflammatory conditions that haven't improved with standard anti-inflammatory protocols

ROS acts on the multiple easily oxidizing cysteine residues contained in KEAP1 and causes conformational changes in KEAP1, thereby preventing NRF2 ubiquitination and promoting its nuclear transposition to initiate the expression of antioxidant defense proteins (127)

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