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But a main function of the kidney is to help filter toxins and waste from the body, "and when the kidneys aren't working properly, they aren't getting rid of drugs like opioids," Novick said

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The result was three to seven

Methods: Tamoxifen-resistant cell lines previously developed and characterized in our laboratory were metabolically profiled with nuclear magnetic resonance spectroscopy (NMR) using cryogenic probe, and the findings were correlated with the expression of genes that encode the key enzymes of the significant metabolites