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Of relevance, recent evidence indicates that SAM exerts anti-inflammatory effects by reducing the expression of the proinflammatory cytokine tumor necrosis factor-alpha (TNF) and increasing the expression of the anti-inflammatory cytokine interleukin 10 (IL-10)

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In addition, those MCL tears which completely tear off the femur and the knee gaps open with the knee out straight, or where the MCL tears off the tibia and retracts towards the joint line, have a high requirement for needing surgery