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Furthermore, based on data from CPS-II, there was no evidence of an increasing risk of COPD with increasing frequency or duration of ST product use: none of the estimates were statistically significant, and the largest point estimate (2.45, 95% CI = 0.777.74) was seen for the least frequent user group, which does not support any dose-response relationship (estimates for the intermedium and the most frequent group were 1.02 and 1.41, respectively.) [65] Footnote 1

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Intrauterine exposure to nicotine through maternal vaping disrupts embryonic lung and skeletal development via the Kcnj2 potassium channel, Developmental Biology, Volume 501, 2023, Pages 111-123, ISSN 0012-1606, Discover what quickening is in pregnancy, when to expect it, and what it feels like