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Vitamin B12 Shot B12 is an essential vitamin that you can become deficient in, particularly if you follow a restricted or special diet, if youre pregnant or breastfeeding, smoke or drink more than you should or are elderly

This further suggests that the effect of CHAC1 on ferroptosis induction is at least in part due to its effect on the mitochondria, as only cysteine restriction and not GPX4 inhibition-induced ferroptosis has an established mitochondrial component 15

Here is a rough timeline people describe