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When alterations in nutritional status or mitochondrial dysfunction induce changes in the NAD + /NADH and AMP/ATP ratios, the expression of the PGC-1 coactivator family of proteins increases, and these proteins interact with nuclear respiratory factor (NRF)1 and 2, thereby activating the phosphorylation of AMPK and upregulating mitochondrial gene expression, transcription and replication [38, 39]

Stress management techniques: Incorporating practices like mindfulness and meditation to reduce stress, can impact thyroid health

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