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Toward a new paradigm for the efficient in vitro - in vivo extrapolation of metabolic clearance in humans from hepatocyte data

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Full disclosure, I'm a clinician through and through, so my experience is observing people

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Activated endothelium displays increased TF expression, triggering extrinsic and intrinsic coagulation cascades and contributing to a prothrombotic endovascular surface [80]

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