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In oocytes, mitochondrial renewal does not occur through cell division because of prolonged cell cycle arrest in meiosis [138], making these cells highly dependent on mitophagy to maintain mitochondrial quality and function [139]

By changing free ferulic acid to 4-vinyl guaiacol and acetovanillone, Streptomyces tunisiensis DSM42037 notably exhibited remarkable catalytic efficiency, with molar biotransformation resulting in 97% and 83%, respectively (Zhou et al., 2020)

1, 2 IGF-1R is primarily activated by its high-affinity ligands, IGF-1 and IGF-2, though it can also bind insulin with lower affinity