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Naturally occurring skin-whitening agents for inhibiting melanogenesis Naturally occurring skin-whitening agents exert their effects by regulating melanin production through a number of mechanisms, including inhibiting the expression and activity of TYR and suppressing the uptake and distribution of melanosomes

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In recent years, understanding of the aetiology of the disease has improved with a number of studies investigating the molecular mechanism behind the loss of melanocytes in vitiligo [37]