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Mitochondria serve as the factory for cellular ROS production, mainly through synthesis in the ETC

It supports the vascular supply to peripheral tissue at a time when circulation may be a limiting factor

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Studies have revealed that radiation exposure decreases expression of aromatase and suppresses expression of CYP450SCC and ABP, whereas L-carnitine treatment prior and during radiation exposure can inhibit these suppressions and increase reduced expression of aromatase mRNA (69)