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72 Interestingly, several ASD animal models, including Fmrp -mutant, 167 Mecp2 -mutant, 113 Tsc1/2 -mutant, 226 Pten -mutant, 227 Shank3 -knockout, 211,228 Nlgn3 -knockout 229 and 16p11.2-knockout models, 26 have shown dysregulation of mGluRs and abnormal mGluR-dependent LTD

(4) Sai-Chuen Fu, Yau-Chuk Cheuk, Wai-Yin Vivien Chiu, Shu-Hang Yung, et al (2015) Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction Journal of Orthopaedic Research, 2015 Jul, Volume 33 (Issue 7), Pages 1024-33

Needle size, for example, is exceedingly small, making subcutaneous administration at home relatively painless compared to larger needle gauges used with thicker medications for things like blood draws

Patients in BE COMPLETE were randomized 2:1 to SC bimekizumab 160 mg Q4W or placebo (Supplementary Figure S1)