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Mice with a deficiency of key components in the NF-B pathway die as a result of massive hepatocyte apoptosis induced by TNF 37,38 , supporting the critical role of maintenance of hepatocyte NF-B pathway in protecting against TNF cytotoxicity

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Also, an analysis by meta-analysis of controlled trials has shown that low-carb diets have a significant impact on BMI, HOMA-IR (insulin resistance), and cholesterol content, especially when interventions last more than four weeks [76]

10.1074/jbc.M111.236281 35 GuoM.LiuH.YuY.ZhuX.XieH.WeiC.et al (2023)