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If we assume that the parents of the 4 cases described here are asymptomatic heterozygous carriers, the probability of each couple having a child with KS is 25% per pregnancy,3 hence the importance of providing patients and their parents with genetic counseling

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of those smoking up to a pack a day, 34 will not live to 65, and of those smoking two packs a day or more, 41 will die before 65. Wallace said statistics show smokers who quit move into a lower mortality rate, but never back to the original non-smoker level

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