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Smuggling counteracts the positive effects of limiting local demand as illicit products tend to be more harmful to consumers, are sold to minors, and cost governments billions of dollars in lost tax revenue

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This is useful to know when dealing with a complex mixture of different compounds, Autumn Shelton, partner and chief financial officer of Autumn Brands, a cannabis business located in Carpinteria, CA, explained that because cannabis is made up of over a hundred cannabinoids and other compounds, its difficult to make broad claims about its effects especially based on a study with a small number of participants