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A structure-based assignment of the glutathione activator site without transition-state analogues is much more difficult because of labile GSH interactions 2 that likely depend not only on the presence of the first glutathione moiety but also on conformational changes of the glutathionylated enzyme 3,12,37,44

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Micha Karliski: nothing to disclose Poster Session II - DIGITAL TRANSFORMATION, AI AND ROBOTICS 07.00 - DIGITAL TRANSFORMATION, AI AND ROBOTICS - 07.01 - TECHNOLOGY INNOVATIONS: ROBOTS, VIRTUAL REALITY, ARTIFICIAL INTELLIGENCE AND MORE P894 - ESOC25-982 ARTIFICIAL INTELLIGENCE-BASED SPATIO-TEMPORAL ANALYSIS FOR MODIFIED THROMBOLYSIS IN CEREBRAL INFARCTION SCORING Jichang Luo 1 , Botao Hou 2 , Wanying Liao 3 , Renjie Yang 4 , Tao Wang 4 , Xuesong Bai 4 , Jie Wang 4 , Haozhi Gong 4 , Tianhua Li 4 , Bin Yang 4 , Yu Zhang 2 , Liqun Jiao 4 , Xi Chen 2 1 Department of Neurosurgery, Xuanwu Hospital, Capital Medical University., Beijing, China, 2 State Key Laboratory of Industrial Control Technology, College of Control Science and Engineering, Zhejiang University, Hangzhou, China, Hangzhou, China, 3 Department of Gastroenterology, Peking Union Medical College Hospital (PUMCH), Beijing, China, 4 Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China, Beijing, China Background and Aims: Acute ischemic stroke (AIS) leads to significant global mortality and disability

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