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When IgG4-RD involves the central nervous system or surrounding areas, it may cause: Persistent headaches Eye pain or swelling Facial numbness Neurological symptoms like vision or hearing changes Chronic sinus problems These symptoms may resemble migraines, tension-type headaches, or sinus infections, which is why understanding the link between IgG4-RD and chronic headaches is essential

when compromised, digestive contents leak through, triggering inflammation

For those managing eczema alongside anxiety or other stress-related conditions, the gut-brain-skin axis represents another relevant dimension