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When Alcohol and Zoloft are combined, it may: Amplify the Zoloft side effects of both substances Lead to heightened drowsiness, dizziness, and impaired coordination Create a cycle of increasing medication use, which may lead to psychological dependence on both substances Impair judgment and decision-making Lead to increased tolerance and dependence Mixing Zoloft and Drugs Zoloft itself is not considered addictive and generally does not produce a high or lead to substance use disorder

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