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And for A1298C, the enzyme activity of heterozygous and homozygous mutant individuals are respectively 83 and 61% of the wild-type subjects 15 , as shown in Fig

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In recent years, natural bioactives derived from plants, microbes, and animals have gained increasing attention as complementary and alternative therapeutic options due to their ability to influence hormonal, metabolic, and inflammatory pathways central to PCOS ( Table 2