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518 In the 2018 National Health and Wellness Survey, nearly 13% of dementia caregivers in the United States indicated absence from work in the past seven days due to a health problem compared with 6% of dementia caregivers in Japan and 10% of dementia caregivers across France, Germany, Italy, Spain and the United Kingdom

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In the event that impacted product is administered to a patient, there is an increased risk that severe adverse events, such as invasive bacterial infection, including bacterial meningitis, septicemia, and limited adverse events such as fever, chills, malaise, and cutaneous abscess may occur

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