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DVT pathogenesis is classically explained by Virchows Triad three interacting factors: Venous stasis (immobility, prolonged bed rest, long-haul travel, heart failure, obesity, paralysis) Endothelial injury (trauma, surgery, central venous catheters, prior DVT, vasculitis) Hypercoagulability (inherited thrombophilias Factor V Leiden mutation [D68.51], prothrombin G20210A mutation [D68.52], antiphospholipid syndrome [D68.61]

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222

Pernicious anaemia , an autoimmune condition affecting approximately 0.1-0.2% of the UK population (higher in older adults), destroys gastric parietal cells that produce intrinsic factora protein essential for B12 absorption in the terminal ileum

Its action is confined to fat tissue