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it undergoes changes throughout an individuals life span, influenced by various factors including the quality of diet (especially long-term dietary habits) environmental conditions, age, physiological state, and certain pharmacological interventions (23)

Pathogen recognition receptors: ligands and signaling pathways by toll-like receptors

However, the symptoms can vary significantly over time, and most patients can be managed effectively with physical therapy, anti-inflammatory medication, and epidural injections without ever needing surgery

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