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HIV medications Some HIV medications, especially certain protease inhibitors and non-nucleoside reverse transcriptase inhibitors, can affect the levels of birth control hormones in the body, either increasing or decreasing their presence, which could impact their effectiveness

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To further explore this citrate method Bally et al., studied the effect of proton gradient by replacing the intraliposomal solution to HEPES buffer pH (7.0) from 300 mm citrate buffer (pH 4.0), keeping the internal pH undisturbed