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A major benefit of implementing an in silico approach to investigating quinone metabolism is the ability to simulate and visualise radical species, such as superoxide, in real time, as this is essentially inaccessible experimentally both in vitro and in vivo

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Electrocardiogram showing clinically significant abnormalities or any history of resuscitated cardiac arrest or presence of an automated internal cardioverter-defibrillator

Since the subjects were block-randomized and technicians were blinded to the treatment, it is highly unlikely that mitochondrial sample preparations, contamination of samples, substrates fed to the mitochondria or the performance of high-resolution respirometers influenced these results