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When the derivation described by Kitz and Wilson [44] for irreversible inactivation was applied to the experimental data, only at low inhibitor concentration, the secondary plot expressing k obs as a function of inhibitor concentration followed Equation 2: where K I represents the dissociation constant of the inhibitor, and k i is the first-order rate constant for irreversible inactivation

I., Durn M., Arias J

Comparative evaluation reveals that while PRP and MSCs demonstrate similar short-term results, neither achieves complete disc structural restoration, and long-term trajectories remain unclear [42]