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The duration THC remains in a teenagers system exhibits significant variability, influenced by a myriad of factors including the frequency of cannabis use, metabolic rate, body fat percentage, and individual biological differences

As one review stated, Nicotine is the addictive chemical in tobacco smoke, but its involvement in smoking-related harm (outside pregnancy) is very small, if any, compared to cigarette smoking. Another systematic review pointed out that nicotine can have a variety of potential health effects, from raising ones cardiovascular risk to causing birth defects in pregnant women

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